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Covid-19: Serum Vaccine Covishield Frequently Asked Questions | India News


NEW DELHI: AstraZeneca signed a licensing agreement with the Serum Institute of India last year to produce 1 billion doses of Oxford University’s Covid-19 vaccine for low-income countries.
The deal was finalized long before the vaccine showed its effectiveness in fighting the Covid-19 virus.
Covishield or AZD-1222 uses a viral vector made from a weakened strain of the common cold virus (adenovirus), which contains genetic material similar to SARS-COV-2. After administration, the body’s defenses recognize the spike protein and prepare antibodies to evade infection.
It was one of the first two vaccines, the other Covaxin from Bharat Biotech, to gain approval in India.
Here are the answers to some of the most frequently asked questions about the vaccine: –
When should I take my second dose?
On May 13, the Union Ministry of Health increased the time interval between the two doses of Covishield to 12-16 weeks from the previous 6-8 weeks, based on the recommendation of an expert panel.
According to the initial permission granted by the Comptroller General of Medicines of India (DGCI), the second dose of Covishield was to be administered 4-6 weeks after the first dose.
Should pregnant women get vaccinated?
While pregnancy puts women at higher risk for severe Covid-19, there is very little data available to assess the safety of the vaccine during pregnancy.
Pregnant women can receive the vaccine if the benefit of vaccinating a pregnant woman outweighs the potential risks of the vaccine.
For this reason, pregnant women at high risk of exposure to SARS-CoV-2 (for example, healthcare workers) or who have comorbidities that increase their risk of serious illness, can be vaccinated in consultation with their healthcare provider.
Who is the vaccine not recommended for??
People with a history of severe allergic reactions to any component of the vaccine should not take it.
The vaccine is not recommended for people under 18 years of age pending the results of additional studies.
What is the recommended dosage?
The recommended dose is two doses intramuscularly (0.5 ml each).
Can I take a single dose of Covishield vaccine?
Additional research is needed to understand the potential longer-term protection after a single dose.
What side effects can I face after getting vaccinated?
A person may develop some symptoms such as pain, heat, itching, bruising, fatigue, chills, fever, nausea, muscle aches, lumps, and discomfort.
Serious side effects like extremely high temperature (over 102 degrees Farhenheit), cough, shortness of breath, nervous problems, anaphylaxis are possible, although rare. It should be noted that serious reactions seen during clinical studies were ruled out as being unrelated to the vaccine.
Can I take one dose of Covishield and one dose of Pfizeror Covaxin?
While some media reports have claimed that India may begin trials “in a few weeks” to see if mixing two different Covid-19 vaccines can help boost the immune response to the virus, the government has denied doing so at this stage. .
Is Covishield safe?
The WHO has included two versions of the vaccine, produced by AstraZeneca-SKBio (Republic of Korea) and the Serum Institute of India, for emergency use. When the vaccine was submitted for consideration by the WHO Strategic Advisory Group of Experts on Immunization (SAGE), the European Medicines Agency (EMA) had reviewed it.
The EMA has carefully evaluated the data on the quality, safety and efficacy of the vaccine and has recommended granting a conditional marketing authorization for people over 18 years of age.
What is the efficacy of the vaccine?
The Covid-19 vaccine is 63.09% effective against symptomatic SARS-CoV-2 infection.
Longer dose intervals within the 8-12 week range are associated with higher vaccine efficacy.
Does it work against new variants?
Yes, it works against newer variants, although more studies are underway to determine if the newer variants cause a change in efficacy.

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