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Black fungus: Center issues advice on the treatment of mucormycosis in patients with Covid | India News


NEW DELHI: Mucormycosis, a fungal infection found in Covid-19 patients with uncontrolled diabetes and prolonged stay in the intensive care unit (ICU), can become fatal if left untreated, the Center said Sunday.
In an advisory, he also said that the fungal infection mainly affects people who take drugs that reduce their ability to fight environmental pathogens.
The Indian Council of Medical Research (ICMR) and the Union Ministry of Health published the advisory based on tests for the detection, diagnosis and treatment of the disease.
“Mucormycosis, if not cared for, can become fatal. The sinuses or lungs of these individuals are affected after fungal spores are inhaled from the air,” he said.
Warning symptoms include pain and redness around the eyes and nose, fever, headache, cough, shortness of breath, vomiting blood and altered mental status, the advisory said.
In Covid-19 patients with diabetes and immunosuppressed individuals, mucormycosis should be suspected if there is sinusitis, facial pain or numbness on one side, blackish discoloration over the bridge of the nose or palate, toothache, blurred or double vision with pain. , skin injury, thrombosis, chest pain and worsening of respiratory symptoms, he said.
The main risk factors for this disease include uncontrolled diabetes mellitus, steroid immunosuppression, prolonged ICU stay, malignancy, and voriconazole therapy, the ICMR Ministry of Health advisory indicated.
To prevent the disease, the blood glucose level should be controlled after discharge from Covid and also in diabetic patients; steroids should be used wisely at the correct time, dose, and duration; clean sterile water should be used in humidifiers during oxygen therapy; and antibiotics and antifungal drugs must be used correctly, he said.
The disease can be managed by controlling diabetes, discontinuing immunomodulatory medications, reducing steroids, and extensive surgical debridement, to remove all necrotic materials, according to the advisory.
Medical treatment includes installation of a peripherally inserted central catheter, maintenance of adequate systemic hydration, infusion of normal saline intravenously prior to amphotericin B infusion, and antifungal therapy for at least six weeks, in addition to monitoring clinically the patient with radio imaging to determine response and detect disease progression. saying.

Times of India