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Coronavirus Vaccine News: The First Covid-19 Vaccine Tested on People in the US USA It is promising | World News


The first coronavirus vaccine to be tested in people in the United States appears to be safe and capable of stimulating an immune response against the virus, its manufacturer, Moderna, announced Monday. The findings are based on the results of the first eight people who received two doses of the vaccine, as of March.
Those people, healthy volunteers, made antibodies that were then tested on human cells in the laboratory and were able to stop virus replication, the key requirement for an effective vaccine. The levels of the so-called neutralizing antibodies matched the levels found in patients who had recovered after contracting the virus. Moderna has said that the second phase with 600 people will start soon, and a third phase that will begin in July with thousands of healthy people. The FDA gave Moderna the go-ahead for Phase II earlier this month.

If those trials go well, a vaccine could be available for widespread use later this year or early 2021, the firm’s chief medical officer, Tal Zaks said.
Three doses of the vaccine were tested: low, medium, and high. These initial results are based on low and medium dose tests. The only adverse effect at these doses was redness and pain in the arm of a patient where the injection was given. But at the highest dose, three patients had fever, muscles and headaches, Zaks said, adding that the symptoms disappeared after a day.
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But the high dose is being phased out of future studies, not so much because of side effects but because the lower doses seem to work so well that the high dose is not necessary. “Lower the dose, the more vaccines we can produce,” Zaks said. Moderna’s shares rose 40% in premarket operations.
In video: The first Covid-19 vaccine in the USA. USA Shows promising results

Times of India